Thanks EmuZombie and Andrew for sending this in. While over at the nvidia website to get a driver for a friend, I noticed that they're ready to officially release the Detonator 4 drivers for windows 2000/XP. It has this listed:
Windows 2000 Driver (v21.80)
Self Extracting Installer
Release Date: 9/10/2001
Version 21.80
Non-WHQL Certified
Although the link still points to the Detonator 4 12.41 drivers it does show that they are ready to switch over for the release date of tomorrow.